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Natural and Synthetic Drug Biological Activity in Modulating Immune System
A special issue of Life (ISSN 2075-1729).
Deadline for manuscript submissions: 23 December 2022.
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Special Issue Editors

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Special Issue Information
Dear Colleagues,
Due to advancements in molecular biology, human diseases can be elucidated more clearly, creating a rise in the use of biomedicines and precision medicines. At the same time, the increasingly common discovery of natural, semi-synthetic and synthetic compounds has equipped the pharmaceutical industry with more ammunition against diseases with various pathophysiologies. However, many diseases and disorders still lack effective medication with which they can be controlled. This unsatisfactory situation has prompted researchers and clinicians to pursue the use of more bioactive natural/synthetic compounds.
Aside from this, the immune system consists of a complex of cells and signal pathways that maintain homeostasis within the human body. Current evidence suggests that immune system imbalance can cause various diseases, ranging from inflammatory diseases to cancers. Currently, an increasing number of bioactive natural/synthetic compounds are being proven to be effective in controlling diseases via affecting the immune system in terms of reactive oxygen species, oxidative stress and apoptosis. However, many primary or secondary immune-related diseases and cancers still require alternative remedies. Herein, this Special Issue invites all researchers and clinicians to publish works concerning the following fields:

Original research/review articles concerning the bioactivity of natural/synthetic compounds in a certain immune-related disease or cancer;
Original research/review articles concerning how bioactive natural/synthetic compounds exert their therapeutic effect via modulating immune microenvironments;
Original research/ review articles concerning how to refine the bioactive natural/synthetic compounds to make them more potent;
Pre-clinical or clinical studies concerning bioactive natural/synthetic compounds regarding their safety or effectivity in treating immune-related diseases or cancers;
Review articles concerning the bioactivity of a certain natural/synthetic compound in different immune-related diseases or cancers.

Dr. Chi-Chien Lin
Dr. Che Hsueh Yang
【the学术橙｜SCI期刊投稿 | 专刊 "NSDBAMIS"】Guest Editors
Manuscript Submission Information
Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
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